What is the totality of evidence you refer to when claiming that switching to IQOS presents less risk than continued smoking?

The totality of evidence includes PMI’s clinical data (we conducted 10 clinical studies with thousands of participants in the US, UK, Japan and Poland), aerosol chemistry, and data from 18 nonclinical studies. The totality of evidence demonstrates that switching completely to IQOS, while not risk-free, presents less risk of harm compared with continuing to smoke cigarettes. For further information, you can visit https://www.pmiscience.com